Antidiabetic effect of Withania coagulans in experimental rats

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چکیده

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Antidiabetic and antihyperlipidemic activity of hydroalcoholic extract of Withania coagulans Dunal dried fruit in experimental rat models

OBJECTIVE Evaluation of antidiabetic potential of the hydroalcoholic extract of Withania coagulans Dunal dried fruit (WCDF) alone and in combination with glipizide, in streptozotocin-induced diabetes, and evaluation of possible antihyperlipidemic activity of the same extract in high-cholesterol diet-induced hyperlipidemia, in albino rats. MATERIALS AND METHODS Experimental diabetes was induce...

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Neuroprotective effects of Withania coagulans root extract on CA1 hippocampus following cerebral ischemia in rats

Objective: Oxygen free radicals may be implicated in the pathogenesis of ischemia reperfusion damage. The beneficial effects of antioxidant nutrients, as well as complex plant extracts, on cerebral ischemia-reperfusion injuries are well known. This study was conducted to determine the effects of the hydro-alcoholic root extract of Withania coagulans on CA1 hippocampus oxidative damages followin...

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Neuroprotective effects of Withania coagulans root extract on CA1 hippocampus following cerebral ischemia in rats

OBJECTIVE Oxygen free radicals may be implicated in the pathogenesis of ischemia reperfusion damage. The beneficial effects of antioxidant nutrients, as well as complex plant extracts, on cerebral ischemia-reperfusion injuries are well known. This study was conducted to determine the effects of the hydro-alcoholic root extract of Withania coagulans on CA1 hippocampus oxidative damages following...

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ژورنال

عنوان ژورنال: Indian Journal of Clinical Biochemistry

سال: 2009

ISSN: 0970-1915,0974-0422

DOI: 10.1007/s12291-009-0015-0